Mechanistic engineering of celastrol liposomes induces ferroptosis and apoptosis by directly targeting VDAC2 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of most common and deadliest malignancies. Celastrol (Cel), a natural product derived from the Tripterygium wilfordii plant, has been extensively researched for its potential effectiveness in fighting cancer. However, its clinical application has been hindered b...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Piao Luo, Qian Zhang, Shuo Shen, Yehai An, Lixia Yuan, Yin-Kwan Wong, Sizhe Huang, Shaohui Huang, Jingnan Huang, Guangqing Cheng, Jiahang Tian, Yu Chen, Xiaoyong Zhang, Weiguang Li, Songqi He, Jigang Wang, Qingfeng Du
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	KeAi Communications Co., Ltd. 2023-11-01
Sarja:	Asian Journal of Pharmaceutical Sciences
Aiheet:	Celastrol VDAC2 Ferroptosis Apoptosis Hepatocellular carcinoma Liposomes
Linkit:	http://www.sciencedirect.com/science/article/pii/S1818087623001009
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