Elucidation of a Novel Dual Binding Site on Tubulin: Theoretical Insights and Prospective Hybrid Inhibitors
<b>Background/Objectives:</b> Microtubule-targeting agents remain foundational components of anticancer chemotherapy, yet their clinical utility is constrained by resistance and toxicity. <b>Methods:</b> Here, we present a theoretical exploration of a plausible “dual” binding pocket that spans the α...
Shranjeno v:
| Principais autores: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI AG
2025-12-01
|
| Serija: | Pharmaceuticals |
| Teme: | |
| Online dostop: | https://www.mdpi.com/1424-8247/19/1/3 |
| Oznake: |
Brez oznak, prvi označite!
|