Macrophage-derived mir-100-5p orchestrates synovial proliferation and inflammation in rheumatoid arthritis through mTOR signaling

Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovial inflammation, causing substantial disability and reducing life quality. While macrophages are widely appreciated as a master regulator in the inflammatory response of RA, the precise mechanisms u...

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Autores principales:	Huan Liu, Yuehong Chen, Yupeng Huang, Ling Wei, Jingjing Ran, Qianwei Li, Yunru Tian, Zhongling Luo, Leiyi Yang, Hongjiang Liu, Geng Yin, Qibing Xie
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-04-01
Colección:	Journal of Nanobiotechnology
Materias:	Rheumatoid arthritis Macrophages Extracellular vesicles miR-100-5p mTOR
Acceso en línea:	https://doi.org/10.1186/s12951-024-02444-1
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