Computational Investigation Identifies mTOR as a Primary Binding Target of Medicarpin in Cholangiocarcinoma: Insights from Network Pharmacology and Molecular Docking

Background: Cholangiocarcinoma (CCA) is an aggressive cancer of biliary tract with poor prognosis and limited therapeutic alternatives. While targeted medicines only benefit a small subset of patients with specific genetic modifications, conventional chemotherapy offers negligible survival advantage...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sirinya Sitthirak, Aman Tedasen, Yanisa Rattanapan, Thitinat Duangchan, Hasaya Dokduang, Nawanwat C. Pattaranggoon, Krittamate Saisuwan, Watcharin Loilome, Nisana Namwat
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-11-01
Цуврал:	Life
Нөхцлүүд:	medicarpin cholangiocarcinoma ADME network pharmacology molecular docking signaling pathways
Онлайн хандалт:	https://www.mdpi.com/2075-1729/15/12/1828
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!