Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice

The occurrence of lipotoxicity during obesity-associated cardiomyopathy is detrimental to health. Salvianolic acid A (SAA), a natural polyphenol extract of Salvia miltiorrhiza Bunge (Danshen in China), is known to be cardioprotective. However, its clinical benefits against obesity-associated cardiom...

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Hlavní autoři:	Zhen Yang, Yanli Chen, Zhaoyuan Yan, Tian Tian Xu, Xiangyao Wu, Aiwen Pi, Qingsheng Liu, Hui Chai, Songtao Li, Xiaobing Dou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-03-01
Edice:	Frontiers in Pharmacology
Témata:	salvianolic acid A lipotoxicity myocardial injury TLR4 MAPKs
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.627123/full
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