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Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Abstract Background The cGAS-STING signaling pathway is an essential section of the natural immune system. In recent years, an increasing number of studies have shown a strong link between abnormal activation of the cGAS-STING signaling pathway, a natural immune pathway mediated by the nucleic acid...

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Kaydedildi:
Asıl Yazarlar: Jincai Wen, Wenqing Mu, Hui Li, Yulu Yan, Xiaoyan Zhan, Wei Luo, Zhongxia Wang, Wen Kan, Jia Zhao, Siwen Hui, Ping He, Shuanglin Qin, Yingjie Xu, Ping Zhang, Xiaohe Xiao, Guang Xu, Zhaofang Bai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2023-12-01
Seri Bilgileri:Molecular Medicine
Konular:
Glabridin
cGAS-STING
IRF3
Autoimmune diseases
Type I interferon
Online Erişim:https://doi.org/10.1186/s10020-023-00754-y
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