Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Abstract Background The cGAS-STING signaling pathway is an essential section of the natural immune system. In recent years, an increasing number of studies have shown a strong link between abnormal activation of the cGAS-STING signaling pathway, a natural immune pathway mediated by the nucleic acid...

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Principais autores:	Jincai Wen, Wenqing Mu, Hui Li, Yulu Yan, Xiaoyan Zhan, Wei Luo, Zhongxia Wang, Wen Kan, Jia Zhao, Siwen Hui, Ping He, Shuanglin Qin, Yingjie Xu, Ping Zhang, Xiaohe Xiao, Guang Xu, Zhaofang Bai
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2023-12-01
Serija:	Molecular Medicine
Teme:	Glabridin cGAS-STING IRF3 Autoimmune diseases Type I interferon
Online dostop:	https://doi.org/10.1186/s10020-023-00754-y
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