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CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx

Abstract Background The main chromatin unit, the nucleosome, can be modulated by the incorporation of histone variants that, in combination with posttranslational histones modifications, determine epigenetics properties of chromatin. Understanding the mechanism that creates a histone variants landsc...

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Principais autores: Viacheslav M. Morozov, Serena Giovinazzi, Alexander M. Ishov
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-12-01
Serier:Epigenetics & Chromatin
Fag:
Histone chaperone Daxx
H3.3
CENP-B
Centromere
SUMO
Chromatin
Online adgang:http://link.springer.com/article/10.1186/s13072-017-0164-y
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