CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading

Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigenetically by a centromere-specific histone H3 varia...

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Autores principales:	Dongqing Pan, Kerstin Klare, Arsen Petrovic, Annika Take, Kai Walstein, Priyanka Singh, Arnaud Rondelet, Alexander W Bird, Andrea Musacchio
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2017-01-01
Colección:	eLife
Materias:	kinetochore centromere cell cycle CENP-A chromatin
Acceso en línea:	https://elifesciences.org/articles/23352
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