KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors

Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNAs are encoded in the latency-associated region. Knockdown of KSHV miR-K12-3 and miR-K12-11 increased expression of lytic genes in BC-3 cells, and increased virus production from latently infected BCBL-1 cells. Furthermore, iSLK cells infected wi...

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Bibliografische Detailangaben

Hauptverfasser:	Karlie Plaisance-Bonstaff, Hong Seok Choi, Tyler Beals, Brian J. Krueger, Isaac W. Boss, Lauren A. Gay, Irina Haecker, Jianhong Hu, Rolf Renne
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2014-10-01
Schriftenreihe:	Viruses
Schlagworte:	KSHV miRNA lytic reactivation latency
Online-Zugang:	http://www.mdpi.com/1999-4915/6/10/4005
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