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Echinomycin as a promising therapeutic agent against KSHV-related malignancies

Abstract Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiologic agent of several human cancers, including Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL), which preferentially arise in immunocompromised patients while lack of effective therapeutic options. Oncoproteins Myc and hyp...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jungang Chen, Zhen Lin, Jiao Song, Karlie Plaisance-Bonstaff, Jennifer James, Shengyu Mu, Steven R. Post, Lu Dai, Zhiqiang Qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-05-01
Schriftenreihe:Journal of Hematology & Oncology
Schlagworte:
KSHV
HHV-8
Myc
HIF1α
Echinomycin
Online-Zugang:https://doi.org/10.1186/s13045-023-01441-5
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