Reprogramming microglia in sepsis-associated encephalopathy: from pathological dysfunction to therapeutic restoration

Microglia, being the resident immunological sentinels of the central nervous system (CNS), play a critical role in both the pathogenesis and progression of CNS health and disease. In sepsis-associated encephalopathy (SAE), it is increasingly evident that the phenotype and function of microglia may c...

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Principais autores:	Chen He, Hui Shi, Zhijie Yu, Zhiqiang Jiao, Jin Li, Fei Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-04-01
coleção:	Frontiers in Immunology
Assuntos:	microglia sepsis-associated encephalopathy cellular reprogramming neuroinflammation epigenetic regulation inflammatory response
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1804207/full
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