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A machine learning-derived hypoxia- and lactylation-associated gene signature for prognostic stratification and immune landscape characterization in lung adenocarcinoma

Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related death worldwide. Hypoxia and histone lactylation are emerging regulators of tumor progression and immune escape. However, their concurrent enrichment and immune-associated features in lung adenocarcin...

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Hlavní autoři: Guannan Wang, Yanan Wang, Hongfeng Wu, Hua Huang, Xuanguang Li, Wenhao Zhao, Yongwen Li, Hongyu Liu, Jun Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-05-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1720885/full
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