Integrated bulk and single-cell RNA sequencing identifies an aneuploidy-based gene signature to predict sensitivity of lung adenocarcinoma to traditional chemotherapy drugs and patients’ prognosis

Background Patients with lung adenocarcinoma (LUAD) often develop a poor prognosis. Currently, researches on prognostic and immunotherapeutic capacity of aneuploidy-related genes in LUAD are limited. Methods Genes related to aneuploidy were screened based on bulk RNA sequencing data from public data...

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Ngā kaituhi matua:	Xiaobin Wang, Jiakuan Chen, Chaofan Li, Yufei Liu, Shiqun Chen, Feng Lv, Ke Lan, Wei He, Hongsheng Zhu, Liang Xu, Kaiyuan Ma, Haihua Guo
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	PeerJ Inc. 2024-06-01
Rangatū:	PeerJ
Ngā marau:	Aneuploidy Bulk RNA sequencing Single-cell RNA-sequencing Prognostic signature Immunotherapy Lung adenocarcinoma
Urunga tuihono:	https://peerj.com/articles/17545.pdf
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!