The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6

The Hippo signaling pathway regulates tissue growth in Drosophila through the transcriptional coactivator Yorkie (Yki). How Yki activates target gene transcription is poorly understood. Here, we identify Nuclear receptor coactivator 6 (Ncoa6), a subunit of the Trithorax-related (Trr) histone H3 lysi...

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Hlavní autoři:	Yun Qing, Feng Yin, Wei Wang, Yonggang Zheng, Pengfei Guo, Frederick Schozer, Hua Deng, Duojia Pan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2014-07-01
Edice:	eLife
Témata:	Hippo signaling transcription factor growth control histone methylation
On-line přístup:	https://elifesciences.org/articles/02564
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