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EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution

Abstract Background A growing body of research has emphasized 5-hydroxymethylcytosine (5hmC) as an important epigenetic mark. High-resolution methods to detect 5hmC require high sequencing depth and are therefore expensive. Many studies have used enrichment-based methods to detect 5hmC; however, con...

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Principais autores: Jaywon Lee, Dongin Lee, Hwang-Phill Kim, Tae-You Kim, Duhee Bang
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2023-03-01
סדרה:Clinical Epigenetics
נושאים:
5-hydroxymethyl cytosine
Colorectal cancer
Detection
Enrichment
גישה מקוונת:https://doi.org/10.1186/s13148-023-01451-7
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