Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in <i>Drosophila melanogaster</i> Exposed to Dietary Sucrose

Excess dietary carbohydrates are linked to dysregulation of metabolic pathways converging to mitochondria and metabolic inflexibility. Here, we determined the role of the mitochondrial pyruvate carrier (MPC) in the occurrence of this metabolic inflexibility in wild-type (WT) and MPC1-deficient (MPC1...

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Detalhes bibliográficos

Principais autores:	Chloé J. Simard, Mohamed Touaibia, Eric Pierre Allain, Etienne Hebert-Chatelain, Nicolas Pichaud
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-10-01
coleção:	Metabolites
Assuntos:	Drosophila mitochondrial pyruvate carrier mitochondrial respiration homeostasis sucrose metabolomics
Acesso em linha:	https://www.mdpi.com/2218-1989/10/10/411
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