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ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs

ADP-ribosylation factors (ARFs) are GTP-binding proteins that were discovered in the early 1980s, shortly after heterotrimeric GTP-binding proteins (G proteins) and nearly simultaneously with RAS. G proteins formed the basis for the signaling paradigm that has been broadly applied to GTPases, includ...

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Detalhes bibliográficos
Main Authors: Rachel E. Turn, Joel Bryan Dacks, Eric M. Rosenberg, Olivier Soubias, John K. Northup, Paul A. Randazzo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-10-01
Colecção:Frontiers in Molecular Biosciences
Assuntos:
ARF
RAS
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1668286/full
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