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Analysis of human lung mast cells by single cell RNA sequencing

Mast cells are tissue-resident cells playing major roles in homeostasis and disease conditions. Lung mast cells are particularly important in airway inflammatory diseases such as asthma. Human mast cells are classically divided into the subsets MCT and MCTC, where MCT express the mast cell protease...

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Principais autores: Elin Rönnberg, Avinash Ravindran, Luca Mazzurana, Yitao Gong, Jesper Säfholm, Julie Lorent, Olga Dethlefsen, Ann-Charlotte Orre, Mamdoh Al-Ameri, Mikael Adner, Sven-Erik Dahlén, Joakim S. Dahlin, Jenny Mjösberg, Gunnar Nilsson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-03-01
coleção:Frontiers in Immunology
Assuntos:
mast cells (MC)
single cell RNA sequencing
lung
heterogeniety
chymase (CMA1)
cathepsin G (CTSG)
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151754/full
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