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Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans.

While insulin signaling has been extensively studied in Caenorhabditis elegans in the context of ageing and stress response, less is known about the factors underlying the secretion of insulin ligands upstream of the insulin receptor. Activation of the receptor governs the decision whether to progre...

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Bibliografiske detaljer
Principais autores: Ola Billing, Gautam Kao, Peter Naredi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3022011?pdf=render
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