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Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans.

While insulin signaling has been extensively studied in Caenorhabditis elegans in the context of ageing and stress response, less is known about the factors underlying the secretion of insulin ligands upstream of the insulin receptor. Activation of the receptor governs the decision whether to progre...

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Autors principals: Ola Billing, Gautam Kao, Peter Naredi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3022011?pdf=render
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