Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L.

Approximately 30% of patients with Epstein-Barr virus (EBV)-positive advanced nasopharyngeal carcinoma (NPC) display chemoresistance to cisplatin-based regimens, but the underlying mechanisms are unclear. The Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1), a functional homologue o...

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Autors principals:	Guang-Da Yang, Tie-Jun Huang, Li-Xia Peng, Chang-Fu Yang, Ran-Yi Liu, Hong-Bing Huang, Qiao-Qiao Chu, Hong-Jie Yang, Jia-Ling Huang, Zhen-Yu Zhu, Chao-Nan Qian, Bi-Jun Huang
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2013-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC3806812?pdf=render
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