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DGAT2 Plays a Crucial Role to Control ESRRAPROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability

Background Diacylglycerol O-acyltransferase 2 (DGAT2) synthesizes triacylglycerol (TG) from diacylglycerol; therefore, DGAT2 is considered as a therapeutic target for steatosis. However, the consequence of inhibiting DGAT2 is not fully investigated due to side effects including lethality and lipotox...

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Bibliografski detalji
Glavni autori: Yoseob Lee, Yeseong Hwang, Minki Kim, Hyeonuk Jeon, Seyeon Joo, Sungsoon Fang, Jae-Woo Kim
Format: Artigo
Jezik:Inglês
Izdano: Korean Diabetes Association 2024-09-01
Serija:Diabetes & Metabolism Journal
Teme:
Online pristup:http://www.e-dmj.org/upload/pdf/dmj-2023-0368.pdf
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