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DGAT2 Plays a Crucial Role to Control ESRRAPROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability

Background Diacylglycerol O-acyltransferase 2 (DGAT2) synthesizes triacylglycerol (TG) from diacylglycerol; therefore, DGAT2 is considered as a therapeutic target for steatosis. However, the consequence of inhibiting DGAT2 is not fully investigated due to side effects including lethality and lipotox...

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Autori principali: Yoseob Lee, Yeseong Hwang, Minki Kim, Hyeonuk Jeon, Seyeon Joo, Sungsoon Fang, Jae-Woo Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Diabetes Association 2024-09-01
Serie:Diabetes & Metabolism Journal
Soggetti:
carcinoma, hepatocellular
diacylglycerol o-acyltransferase
mitochondria
non-alcoholic fatty liver disease
Accesso online:http://www.e-dmj.org/upload/pdf/dmj-2023-0368.pdf
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