CETP inhibitor evacetrapib enters mouse brain tissue

High levels of plasma cholesterol, especially high levels of low-density lipoprotein cholesterol (LDL-C), have been associated with an increased risk of Alzheimer’s disease. The cholesteryl ester transfer protein (CETP) in plasma distributes cholesteryl esters between lipoproteins and increases LDL-...

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主要な著者:	Jasmine Phénix, Jonathan Côté, Denis Dieme, Sherilyn J. Recinto, Felix Oestereich, Sasen Efrem, Sami Haddad, Michèle Bouchard, Lisa Marie Munter
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2023-07-01
シリーズ:	Frontiers in Pharmacology
主題:	cholesterol evacetrapib brain cholesteryl ester transfer protein (CETP) Alzheimer’s disease PBPK model
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1171937/full
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