Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models

Tubercular Mycobacteria and Legionella pneumophila are the causative agents of potentially fatal respiratory diseases due to their intrinsic pathogenesis but also due to the emergence of antibiotic resistance that limits treatment options. The aim of our study was to explore the antimicrobial activi...

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Hlavní autoři:	Nabil Hanna, Sébastien Kicka, Gianpaolo Chiriano, Christopher Harrison, Hajer Ouertatani Sakouhi, Valentin Trofimov, Agata Kranjc, Jahn Nitschke, Marco Pagni, Pierre Cosson, Hubert Hilbi, Leonardo Scapozza, Thierry Soldati
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-02-01
Edice:	Frontiers in Microbiology
Témata:	Mycobacterium Legionella anti-infective ChemGPS amoebae
On-line přístup:	https://www.frontiersin.org/article/10.3389/fmicb.2020.00266/full
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