Footprint of pancreas infiltrating and circulating immune cells throughout type 1 diabetes development

IntroductionType 1 diabetes (T1D) is defined by immune cell infiltration of the pancreas, in particular the islets of Langerhans, referred to as insulitis, which is especially prominent during the early disease stages in association with decreased beta cell mass. An in-depth understanding of the dyn...

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Hlavní autoři:	Ylke Bruggeman, Pieter-Jan Martens, Gabriele Sassi, Marijke Viaene, Clive H. Wasserfall, Chantal Mathieu, Conny Gysemans
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-11-01
Edice:	Frontiers in Endocrinology
Témata:	type 1 diabetes immunodynamics NOD mouse model single cell RNA sequencing pancreas
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1275316/full
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