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4-Methoxy Sulfonyl Paeonol Inhibits Hepatic Stellate Cell Activation and Liver Fibrosis by Blocking the TGF-β1/Smad, PDGF-BB/MAPK and Akt Signaling Pathways

Liver fibrosis initiates the progression of cirrhosis, and, finally, hepatocellular carcinoma (HCC). The increased proliferation and activation of hepatic stellate cells (HSCs) are crucial for hepatic fibrogenesis. Paeonol is the major vigorous component of Cortex Moutan, a traditional herbal medici...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yi-Jen Liao, Yuan-Hsi Wang, Chao-Lien Liu, Cheng-Chieh Fang, Ming-Hua Hsu, Fat-Moon Suk
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2020-08-01
Saila:Applied Sciences
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2076-3417/10/17/5941
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