Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis

BackgroundHepatocellular Carcinoma (HCC) is a sexually dimorphic cancer, with female sex being independently protective against HCC incidence and progression. The aim of our study was to understand the mechanism of estrogen receptor signaling in driving sex differences in hepatocarcinogenesis.Method...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mamatha Bhat, Elisa Pasini, Chiara Pastrello, Marc Angeli, Cristina Baciu, Mark Abovsky, Angella Coffee, Oyedele Adeyi, Max Kotlyar, Igor Jurisica
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2021-11-01
Цуврал:	Frontiers in Oncology
Нөхцлүүд:	estrogen hepatocellular carcinoma high-throughput network analysis Wnt/b-catenin ESR1
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fonc.2021.777834/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!