Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma
Glioblastoma (GBM) is a high-grade, aggressive brain tumor with dismal median survival time of 15 months. Chromosome 6q (Ch6q) is a hotspot of genomic alterations, which is commonly deleted or hyper-methylated in GBM. Two neighboring genes in this region, QKI and PRKN have been appointed as tumor su...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fcell.2022.931387/full |
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