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Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma

Cellular therapy with chimeric antigen receptor (CAR)-redirected cytotoxic T cells has shown impressive efficacy in the treatment of hematologic malignancies. We explored a regulatory T cell (Treg)-based therapy in the treatment of allergic airway inflammation, a model for asthma, which is character...

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Principais autores: Jelena Skuljec, Markus Chmielewski, Christine Happle, Anika Habener, Mandy Busse, Hinrich Abken, Gesine Hansen
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2017-09-01
丛编:Frontiers in Immunology
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在线阅读:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01125/full
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