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1-methylnicotinamide modulates IL-10 secretion and voriconazole metabolism

BackgroundInflammatory diseases impair the hepatic metabolism of voriconazole (VRC). 1-Methylnicotinamide (1-MNA), a common final metabolite of nicotinamide in the liver, has demonstrated anti-inflammatory effects in recent studies. This study investigated the impact of 1-MNA on VRC metabolism in th...

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Bibliografische Detailangaben
Hauptverfasser: Xiaoyan Deng, Yuanqing Li, Lin Jiang, Xuqiu Xie, Xiaokang Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2025-02-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529660/full
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