Pharmacokinetic Drug Interaction between Tofacitinib and Voriconazole in Rats
Fungal infections are prevalent in patients with immune diseases. Voriconazole, a triazole antifungal drug, inhibits the cytochromes CYP3A4 and CYP2C, and tofacitinib, a Janus kinase inhibitor for the treatment of rheumatoid arthritis, is metabolized by CYP3A4 and CYP2C19 in humans. Here, we investi...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2021-05-01
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| Serie: | Pharmaceutics |
| Soggetti: | |
| Accesso online: | https://www.mdpi.com/1999-4923/13/5/740 |
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