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Cleavage site heterogeneity at the pre-mRNA 3′-untranslated region regulates gene expression in oxidative stress response

The endonucleolytic cleavage step of the eukaryotic mRNA 3′-end processing is considered imprecise, which leads to heterogeneity of cleavage site (CS) with hitherto unknown function. Contrary to popular belief, we show that this imprecision in the cleavage is tightly regulated, resulting in the CS h...

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Hlavní autoři: Feba Shaji, Jamshaid Ali, Rakesh S. Laishram
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-04-01
Edice:Redox Biology
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213231725000783
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