Complement Activation-Related Pathophysiological Changes in Anesthetized Rats: Activator-Dependent Variations of Symptoms and Mediators of Pseudoallergy

Complement (C) activation can underlie the infusion reactions to liposomes and other nanoparticle-based medicines, a hypersensitivity syndrome that can be partially reproduced in animal models. However, the sensitivities and manifestations substantially differ in different species, and C activation...

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Detalhes bibliográficos

Principais autores:	László Dézsi, Tamás Mészáros, Erik Őrfi, Tamás G. Fülöp, Mark Hennies, László Rosivall, Péter Hamar, János Szebeni, Gábor Szénási
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-09-01
coleção:	Molecules
Assuntos:	complement activation infusion reactions zymosan cobra venom factor amphotericin B blood pressure blood cell count thromboxane
Acesso em linha:	https://www.mdpi.com/1420-3049/24/18/3283
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