Immune checkpoint status and oncogenic mutation profiling of rectal cancer after neoadjuvant chemotherapy (KSCC1301‐A2)

Abstract Aim Immune checkpoint inhibitors (ICIs) are less effective in mismatch repair (MMR)‐proficient (pMMR) colorectal cancers (CRCs) than in MMR‐deficient CRCs. Here, we investigated changes in the tumor microenvironment after neoadjuvant chemotherapy (NAC) without radiotherapy in locally advanc...

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Hlavní autoři:	Yu Miyashita, Eiji Oki, Tomohiro Kamori, Yoshito Akagi, Shinichiro Mori, Norifumi Hattori, Kazuma Kobayashi, Mototsugu Shimokawa, Yoshinao Oda, Masaki Mori
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-03-01
Edice:	Annals of Gastroenterological Surgery
Témata:	immune checkpoint inhibitor neoadjuvant chemotherapy next‐generation sequencing rectal cancer tumor microenvironment
On-line přístup:	https://doi.org/10.1002/ags3.12730
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