Immune checkpoint status and oncogenic mutation profiling of rectal cancer after neoadjuvant chemotherapy (KSCC1301‐A2)

Abstract Aim Immune checkpoint inhibitors (ICIs) are less effective in mismatch repair (MMR)‐proficient (pMMR) colorectal cancers (CRCs) than in MMR‐deficient CRCs. Here, we investigated changes in the tumor microenvironment after neoadjuvant chemotherapy (NAC) without radiotherapy in locally advanc...

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主要な著者:	Yu Miyashita, Eiji Oki, Tomohiro Kamori, Yoshito Akagi, Shinichiro Mori, Norifumi Hattori, Kazuma Kobayashi, Mototsugu Shimokawa, Yoshinao Oda, Masaki Mori
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2024-03-01
シリーズ:	Annals of Gastroenterological Surgery
主題:	immune checkpoint inhibitor neoadjuvant chemotherapy next‐generation sequencing rectal cancer tumor microenvironment
オンライン･アクセス:	https://doi.org/10.1002/ags3.12730
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