Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

Microtubules are tubulin polymer structures, which are indispensable for cell growth and division. Its constituent protein β-tubulin has been a common drug target for various diseases including cancer. Colchicine has been used to treat gout, but it has also been an investigational anticancer ag...

Descrición completa

Detalles Bibliográficos

Principais autores:	Urszula Majcher, Greta Klejborowska, Mahshad Moshari, Ewa Maj, Joanna Wietrzyk, Franz Bartl, Jack A. Tuszynski, Adam Huczyński
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2018-11-01
Series:	Cells
Assuntos:	colchicine binding site inhibitor β-tubulin affinity antimitotic agent antiproliferative activity thiocolchicine
Acceso en liña:	https://www.mdpi.com/2073-4409/7/11/192
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!