Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssi

Replication slippage or slipped-strand mispairing involves the misalignment of DNA strands during the replication of repeated DNA sequences, and can lead to genetic rearrangements such as microsatellite instability. Here, we show that PolB and PolD replicative DNA polymerases from the archaeal model...

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Detalhes bibliográficos

Principais autores:	Melissa G. eCastillo-Lizardo, Ghislaine eHenneke, Enrique eViguera
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-08-01
Colecção:	Frontiers in Microbiology
Assuntos:	Archaea DNA polymerases slippage primer-template misalignment strand displacement activity
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00403/full
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