Subchondral bone repair potential of an osteochondral scaffold augmented with BMP-2 or strontium-enriched amorphous calcium phosphate: a co-culture in vitro model

PurposeA collagen/collagen-magnesium-hydroxyapatite (Col/Col-Mg-HA) scaffold is currently used in the clinical practice to address osteochondral lesions (OCL). However, suboptimal bone regeneration still limits its overall reparative potential. The aim of this study was to test in vitro the osteoind...

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Autori principali:	Manuela Salerno, Marta Columbaro, Stefania Pagani, Janis Locs, Jana Vecstaudza, Laura Dolcini, Milena Fini, Gianluca Giavaresi, Giuseppe Filardo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-02-01
Serie:	Frontiers in Medicine
Soggetti:	BMP-2 calcium phosphates mesenchymal stromal cells osteochondral defect scaffold
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1738671/full
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