Subchondral bone repair potential of an osteochondral scaffold augmented with BMP-2 or strontium-enriched amorphous calcium phosphate: a co-culture in vitro model

PurposeA collagen/collagen-magnesium-hydroxyapatite (Col/Col-Mg-HA) scaffold is currently used in the clinical practice to address osteochondral lesions (OCL). However, suboptimal bone regeneration still limits its overall reparative potential. The aim of this study was to test in vitro the osteoind...

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Bibliographic Details

Main Authors:	Manuela Salerno, Marta Columbaro, Stefania Pagani, Janis Locs, Jana Vecstaudza, Laura Dolcini, Milena Fini, Gianluca Giavaresi, Giuseppe Filardo
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-02-01
Series:	Frontiers in Medicine
Subjects:	BMP-2 calcium phosphates mesenchymal stromal cells osteochondral defect scaffold
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1738671/full
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