Nutraceutical Molecules Slow Down Retinal Degeneration, in Tvrm4 Mice a Model of Retinitis Pigmentosa, by Genetic Modulation of Anti-oxidant Pathway

Rhodopsin (RHO) mutations are responsible for 25–40% of the dominant cases of retinitis pigmentosa (RP) with different severity and progression rates. The Tvrm4 mice, heterozygous for an I307N dominant mutation of RHO, display a normal retinal phenotype when raised in ambient light conditions, but u...

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Prif Awduron:	Ilaria Piano, Francesca Corsi, Beatrice Polini, Claudia Gargini
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Frontiers Media S.A. 2022-04-01
Cyfres:	Frontiers in Neuroscience
Pynciau:	nutraceutical treatment photoreceptors degeneration genetic modulation oxidative stress retinitis pigmentosa
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fnins.2022.868750/full
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