“UPRegulation” of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses
Abstract We recently demonstrated that targeting the unfolded protein response (UPR) protein GRP78 down-regulates CD47 expression, resulting in increased tumor macrophage infiltration and inhibited resistance to anti-estrogen therapy. We now show new data indicating that anti-estrogen therapy regula...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2017-08-01
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| Collection: | Biomarker Research |
| Sujets: | |
| Accès en ligne: | http://link.springer.com/article/10.1186/s40364-017-0105-8 |
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