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Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy

Glioblastoma (GBM) is characterized as having high molecular heterogeneity and complexity, which can be well revealed by genomic study. A truly effective treatment for GBM should flexibly address its heterogeneities, complexity, and strong drug resistance. This study was performed to explore the eff...

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Wedi'i Gadw mewn:
Prif Awduron: Xiangjun Tang, Hao Peng, Pengfei Xu, Li Zhang, Rui Fu, Hanjun Tu, Xingrong Guo, Kuanming Huang, Junti Lu, Hu Chen, Zhiqiang Dong, Longjun Dai, Jie Luo, Qianxue Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2022-03-01
Cyfres:Molecular Therapy: Oncolytics
Pynciau:
synthetic mRNA
gene therapy
PTEN
TRAIL
GBM
WES
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2372770522000171
Tagiau: Ychwanegu Tag
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