Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy

Glioblastoma (GBM) is characterized as having high molecular heterogeneity and complexity, which can be well revealed by genomic study. A truly effective treatment for GBM should flexibly address its heterogeneities, complexity, and strong drug resistance. This study was performed to explore the eff...

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Hlavní autoři:	Xiangjun Tang, Hao Peng, Pengfei Xu, Li Zhang, Rui Fu, Hanjun Tu, Xingrong Guo, Kuanming Huang, Junti Lu, Hu Chen, Zhiqiang Dong, Longjun Dai, Jie Luo, Qianxue Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-03-01
Edice:	Molecular Therapy: Oncolytics
Témata:	synthetic mRNA gene therapy PTEN TRAIL GBM WES
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2372770522000171
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