Herpes Simplex Virus 1 Tegument Protein UL46 Inhibits TANK-Binding Kinase 1-Mediated Signaling

ABSTRACT TANK-binding kinase 1 (TBK1) is a key component of the antiviral immunity signaling pathway. It activates downstream interferon regulatory factor 3 (IRF3) and subsequent type I interferon (IFN-I) production. Herpes simplex virus type 1 (HSV-1) can antagonize host antiviral immune responses...

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Detalles Bibliográficos

Principais autores:	Hongjuan You, Sisilia Zheng, Zhiming Huang, Yingying Lin, Qingtang Shen, Chunfu Zheng
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2019-06-01
Series:	mBio
Assuntos:	HSV-1 IRF3 TBK1 UL46 type I IFN
Acceso en liña:	https://journals.asm.org/doi/10.1128/mBio.00919-19
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