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REL-1017 (Esmethadone) Increases Circulating BDNF Levels in Healthy Subjects of a Phase 1 Clinical Study

Brain-derived neurotrophic factor (BDNF), a neurotrophin widely expressed in the central nervous system, exhibits important effects on neural plasticity. BDNF has been implicated in the mechanism of action of ketamine, a N-methyl-d-aspartic acid receptor (NMDAR) antagonist with rapid anti-depressant...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sara De Martin, Daniela Gabbia, Franco Folli, Francesco Bifari, Paolo Fiorina, Nicola Ferri, Stephen Stahl, Charles E. Inturrisi, Marco Pappagallo, Sergio Traversa, Paolo L. Manfredi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021-04-01
Sarja:Frontiers in Pharmacology
Aiheet:
Linkit:https://www.frontiersin.org/articles/10.3389/fphar.2021.671859/full
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