[¹⁸F]fluoride Activation and ¹⁸F-Labelling in Hydrous Conditions—Towards a Microfluidic Synthesis of PET Radiopharmaceuticals

¹⁸F-labelled radiopharmaceuticals are indispensable in positron emission tomography. The critical step in the preparation of ¹⁸F-labelled tracers is the anhydrous F-18 nucleophilic substitution reaction, which involves [¹⁸F]F⁻ anions generated in aqueous m...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Olga Ovdiichuk, Salla Lahdenpohja, Quentin Béen, Laurent Tanguy, Bertrand Kuhnast, Charlotte Collet-Defossez
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-12-01
Schriftenreihe:	Molecules
Schlagworte:	<sup>18</sup>F-radiolabelling radiopharmaceuticals <sup>18</sup>F-activation hydrous radiofluorination microfluidics
Online-Zugang:	https://www.mdpi.com/1420-3049/29/1/147
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