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[<sup>18</sup>F]fluoride Activation and <sup>18</sup>F-Labelling in Hydrous Conditions—Towards a Microfluidic Synthesis of PET Radiopharmaceuticals

<sup>18</sup>F-labelled radiopharmaceuticals are indispensable in positron emission tomography. The critical step in the preparation of <sup>18</sup>F-labelled tracers is the anhydrous F-18 nucleophilic substitution reaction, which involves [<sup>18</sup>F]F<sup>−</sup> anions generated in aqueous m...

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Principais autores: Olga Ovdiichuk, Salla Lahdenpohja, Quentin Béen, Laurent Tanguy, Bertrand Kuhnast, Charlotte Collet-Defossez
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-12-01
Series:Molecules
Assuntos:
<sup>18</sup>F-radiolabelling
radiopharmaceuticals
<sup>18</sup>F-activation
hydrous radiofluorination
microfluidics
Acceso en liña:https://www.mdpi.com/1420-3049/29/1/147
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