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Characterization of the Mitochondrial Genetic Landscape in Abdominal Aortic Aneurysm

Background Abdominal aortic aneurysm (AAA) is a vascular disease with a mortality rate of >80% if ruptured. Mitochondrial dysfunction has been previously implicated in AAA pathogenesis. In this study, we aimed to characterize the mitochondrial genetic landscape in AAA. Methods and Results Whole mito...

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Principais autores: Sakshi Vats, Kristina Sundquist, Yanni Li, Xiao Wang, Mun‐Gwan Hong, Jan Sundquist, Moncef Zarrouk, Anders Gottsäter, Ashfaque A. Memon
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-04-01
coleção:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:
aortic aneurysm
abdominal
computational biology
DNA
mitochondrial
genome
Acesso em linha:https://www.ahajournals.org/doi/10.1161/JAHA.122.029248
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